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7 July 2025: PIB Summary For UPSC

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1. Dr. Jitendra Singh Inaugurates ‘National Biobank’ and India’s own Longitudinal Population Data study at CSIR‑IGIB

(SourcePIB (Press Information Bureau), July, 7, 2025)

Topic: GS Paper 3 – Biotechnology; Health Infrastructure; Scientific Research

Context

  • Within India’s push towards personalized medicine and precision healthcare, the establishment of a national-level biobank marks a major milestone. It complements global initiatives like the UK Biobank, tailored to India’s diverse demographic.

Content

Background

  • National Biobank launch: Inaugurated at CSIR‑IGIB in Delhi by Union MoS (I/C) for Science & Technology, Dr. Jitendra Singh, on 6 July 2025. 

  • Phenome India Project: A longitudinal cohort study that will collect genomic, lifestyle, and clinical data from 10,000 individuals nationwide, representing geographic, ethnic, and socio-economic diversity. 

Key Features & Significance

  • Genome-based healthcare: Enables early diagnosis, precision therapeutics for NCDs (diabetes, cancer, cardiovascular diseases) and rare genetic disorders. India-specific central obesity patterns emphasise the need—some lean individuals have high visceral fat.

  • CRISPR-enabled advances: CSIR‑IGIB actively works on indigenous CRISPR therapies targeting sickle cell anemia, AMR, liver fibrosis, rare disorders. This Biobank will accelerate such research by providing high-resolution, Indian‑context data. 

  • AI synergy: Data generated will fuel AI-driven diagnostics, drug discovery, and gene-guided therapy pipelines.

Institutional & Collaborative Aspects

  • Cross-sector collaborations: Dr. Singh emphasised partnerships across government (DBT), academia, and industry for AMR, drug development, and clinical translation. 

  • CSIR leadership: DG Dr. Kalaiselvi hailed the Biobank as a “baby step” toward self-reliance, potentially rivaling global counterparts. 

  • IGIB’s journey: Since decoding the human genome, IGIB developed 300+ diagnostics, led COVID‑19 sequencing, launched drug genome projects, and expanded into space biology and AI-based pilot assessments.

Analysis for UPSC

  • Health Infrastructure: Addresses infrastructure gaps in genome-based care and public health planning.

  • Biotechnology Ethical & Policy Dimension: Raises data-privacy, bioethics, and equitable access considerations.

  • Science & Technology Focus: Demonstrates India’s focus on cutting-edge CRISPR, AI, quantum tech.

  • Person-centric Research: Aligns with National Health Policy’s call for population-specific strategies.

Way Forward

  • Scale-up: Expand to >100,000 participants, widen geographic and socio-economic coverage.

  • Policy frameworks: Establish robust ethical, consent, data protection, and benefit-sharing policies.

  • Commercialisation: Enable startups and pharma to build diagnostics and therapeutics from the data.

  • Public health impact: Integrate findings into national health missions and disease-prevention strategies

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Practice Question: “Evaluate the significance of establishing a National Biobank in India. How can it shape the future of precision medicine and public health policy in India? Highlight potential challenges and suggest ways to address them.”

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